What is a common reversal agent used for xylazine in cattle?

• A. Atipamezole
• B. Yohimbine
• C. Acepromazine
• D. Flumazenil

Answer: (B)

Yohimbine is a commonly used reversal agent for xylazine in cattle due to its specific action as an alpha-2 adrenergic antagonist. Xylazine acts as a sedative and analgesic by stimulating alpha-2 receptors, leading to sedation and muscle relaxation in the animal. When there is a need to reverse these effects—whether due to prolonged sedation or the need for the animal to regain full consciousness and motor function—yohimbine can effectively block these receptors, reversing the sedative effects of xylazine.

Using yohimbine is particularly advantageous because it is well-studied in ruminants and has a rapid onset of action. This makes it suitable for use in field conditions where immediate recovery is critical. While other drugs listed might have their own uses in veterinary practice, none serve as effective reversal agents for xylazine in cattle like yohimbine does.