Which a2 agonist is commonly used with butorphanol for kid disbudding?

• A. Xylazine
• B. Dexmedetomidine
• C. Acepromazine
• D. Midazolam

Answer: (B)

The commonly used alpha-2 (α2) agonist in combination with butorphanol for kid disbudding is dexmedetomidine. This drug is preferred due to its potent sedative and analgesic effects, which make it particularly effective in managing pain and anxiety during such procedures.

Dexmedetomidine works by stimulating alpha-2 adrenergic receptors in the central nervous system, leading to sedation and a reduction in pain perception. When used alongside butorphanol, which is an opioid agonist, the combination enhances analgesia and sedation, providing a more effective approach to pain management during disbudding in kids.

The other options listed do not serve the same purpose as effectively. Xylazine, while also an α2 agonist, may not be preferred due to its side effects and variability in response among different species. Acepromazine is primarily a tranquilizer and does not provide the analgesic properties necessary for painful procedures. Midazolam, a benzodiazepine, offers sedation and muscle relaxation but lacks the analgesic properties needed when disbudding, making dexmedetomidine the preferred choice in this scenario.