Which four NSAIDs can be used off label in cattle?

• A. Phenylbutazone, Meloxicam, Ketoprofen, Aspirin
• B. Ibuprofen, Carprofen, Aspirin, Naproxen
• C. Flunixin, Butorphanol, Morphine, Gabapentin
• D. Salicylic acid, Phenylbutazone, Flunixin, Meloxicam

Answer: (A)

The four non-steroidal anti-inflammatory drugs (NSAIDs) that can be used off-label in cattle include Phenylbutazone, Meloxicam, Ketoprofen, and Aspirin.

Phenylbutazone is a well-known NSAID that is effective in treating pain and inflammation in various animal species, including cattle. It's often used specifically for musculoskeletal conditions. Meloxicam is another NSAID that has been widely used in veterinary medicine for its analgesic and anti-inflammatory properties, providing relief in cases of pain associated with different conditions in cattle. Ketoprofen is also beneficial for managing pain and has anti-inflammatory effects suitable for treating conditions in cattle. Aspirin, while primarily known for its use in humans, can be effective in cattle when used off-label for conditions requiring reduction of pain and inflammation.

This combination of drugs is recognized for their safety margins and efficacy when used in cattle, making them practical choices in veterinary practice. Although other options may contain medications known for pain relief and anti-inflammatory effects, they may not have the same level of accepted use in cattle or may not be as effective in this specific context.